Transforms the SWATH data from a peptide- to a transition-level table.

Source: R/disaggregate.R

If the SWATH data should be analyzed on transition-level the data needs to be tranformed from peptide-level table to a transition-level table (one row per transition instead of one row per peptide). The columns "aggr_Fragment_Annotation" and "aggr_Peak_Area" are disaggregated into the new columns "Fragmentation" and "Intensity". The following columns are renamed if they exist: FullPeptideName -> PeptideSequence, Charge -> PrecursorCharge, Area -> Intensity, Fragment -> Fragmentation, Sequence -> NakedSequence.

disaggregate(data, all.columns = FALSE)

Arguments

data

A data frame containing SWATH data.

all.columns

Option that all columns are processed. Otherwise only the columns typically needed for downstream analysis are processed.

Value

Returns a data frame containing the SWATH data in a transition-level table.

Author

Peter Blattmann

Examples

{
 data("OpenSWATH_data", package="SWATH2stats")
 data("Study_design", package="SWATH2stats")
 data <- sample_annotation(OpenSWATH_data, Study_design)
 data.filtered.decoy <- filter_mscore(data, 0.01)
 raw <- disaggregate(data.filtered.decoy)
 }
#> Dimension difference: 931, 0
#> The library contains 6 transitions per precursor.
#>                   
#> The data table was transformed into a table containing one row per transition.